Figure 1

Alternative splicing patterns of TPM1 and TPM4 genes. (a) Exon composition of the TPM1 gene and alternative splicing that generates two striated muscle specific isoforms -TPM1α and TPM1κ [26]. (b) Exon composition of TPM4 gene (adapted from avian species as proposed by Fleenor et al. [30] and alternative splicing generate two isoforms in axolotl, TPM4α and a low-molecular weight TPM4 transcript.