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Figure 7 | Regenerative Medicine Research

Figure 7

From: Chronic alcohol ingestion delays skeletal muscle regeneration following injury

Figure 7

Chronic alcohol ingestion and injury drive TGFβ expression. TGFβ1, a regulator of skeletal muscle fibrosis, was induced at (B) 7 days and remained elevated at (C) 14 days following BaCl2 injection. (A) In contrast, TGFβ1 gene levels peaked 2 days following injury in alcohol-fed mice before returning to baseline levels. (D) Despite these discrepancies at the gene level, TGFβ protein content was elevated at each time point following injury and likely drives the robust fibrotic response. Significance was accepted at p ≤ 0.05. *, compared to uninjured group within diet. #, compared to EtOH-fed, uninjured group. $, compared to control-fed, uninjured group.

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